Zacks Investment Research on MSN

Agios Pharmaceuticals stock declines 23% in 6 months: Here's why

Shares of Agios Pharmaceuticals AGIO have plunged 23% over the past six months, primarily due to pipeline and regulatory ...

Why Low Testosterone May Make Sugary Diets Much More Dangerous

A new study explores how decreased testosterone and high fructose intake may interact to influence the development of fatty ...
News4JAX

“Keep Fighting”: Jacksonville 4-year-old with rare disease meets Akshay Bhatia at The Players Championship

A Jacksonville mom reached out after seeing my story on Akshay Bhatia. Her 4-year-old daughter Harlow has the same rare ...
Hosted on MSN

Microbial assembly line makes plastic upcycling programmable

Subscribe to our newsletter for the latest sci-tech news updates. The team engineered the bacterium Pseudomonas putida to convert polyethylene terephthalate, a main class of single-use plastics found ...
The New Indian Express

First-ever oral pill to treat thalassaemia approved

BHUBANESWAR: In a defining breakthrough for the global fight against thalassaemia, the US Food and Drug Administration (FDA) has approved the first-ever oral pill to treat anaemia in adults with the ...
Medical Xpress

Vitamin B1 stops deadly lactate production and opens the door to a new sepsis treatment

Scientists in Ghent have achieved a breakthrough in sepsis research. In a study on mice, the researchers demonstrated that vitamin B1 (thiamine pyrophosphate, TPP) restores mitochondrial energy ...
GEN

Structure of Mitochondrial Pyruvate Carrier Drug Target Bound to Inhibitors Revealed

Scientists led by a team at the Medical Research Council (MRC) Mitochondrial Biology Unit, University of Cambridge, have worked out how a molecular machine found in mitochondria—the “powerhouses” of ...
News Medical

Mitochondrial pyruvate carrier structure solved after fifty years

Fifty years since its discovery, scientists have finally worked out how a molecular machine found in mitochondria, the 'powerhouses' of our cells, allows us to make the fuel we need from sugars, a ...
Nasdaq

Agios’ Phase 3 ACTIVATE-Kids Study of Mitapivat in Children with Pyruvate Kinase (PK) Deficiency Not Regularly Transfused Met Primary Endpoint

– ACTIVATE-Kids is the First Study to Demonstrate Efficacy of an Oral Therapy for Children with PK Deficiency Who Are Not Regularly Transfused – – Safety Results Consistent with Safety Profile for ...
C&EN

Simple ingredients can approximate metabolic cycle without metals or enzymes

Two simple molecules can react to form most of the intermediates in an analog of the modern-day Krebs cycle, without the need for enzymes or metals, according to a new study (Nat. Chem. 2020, DOI: ...
Fonds

Pyruvate : qu'est-ce que c'est ?

Le pyruvate correspond à la forme anion de l'acide pyruvique. C'est également une molécule biologique majeure. Le pyruvate joue un rôle crucial dans le métabolisme énergétique des cellules. En tant ...