T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on ...

Cancer-fighting T cells do not simply "run out of energy." They are molecularly reprogrammed. For years, mitochondrial ...

New research links atopic dermatitis to S1P signalling pathways driving inflammation. Learn how this could shape future ...

Researchers have discovered how mitochondrial stress drives T cell exhaustion and a potential way to restore their ...

Researchers have uncovered a previously hidden “internal brake” on immune cells that limits their ability to fight cancer, ...

The team shows that transient low-dose bortezomib treatment during CAR-T cell manufacturing dampens proteasome-driven heme ...

Researchers discovered a way to keep T cells from wearing out during the fight against cancer, and the approach could make immune-based treatments far more powerful. They found that tumors use a ...

When a virus enters the lungs, the immune system has to react fast. The lung maintains its own community of immune cells ...

Researchers have established a direct experimental link between inflammatory signals in the intestinal lining and the kind of spinal cord damage that mimics multiple sclerosis. A study published in ...

A technique that transforms immune cells into cancer-seeking bloodhounds may overcome a roadblock that has hampered immunotherapy for solid tumors, according to a new study by Stanford Medicine ...