Synaptic pruning is a little like sleep. We know both processes are important to healthy brain function, but we don't know exactly how they happen, nor how to reliably treat problems in the system.

In the Alzheimer’s disease brain, synaptic loss correlates with cognitive decline, and is considered a sign of disease progression. But is synaptic loss always bad? Provocative new data from several ...

Research led by SUNY Downstate Medical Center has identified a brain receptor that appears to initiate adolescent synaptic pruning, a process believed necessary for learning, but one that appears to ...

The first analysis of how synaptic proteins change during early development reveals differences between mice and marmosets but also what's different in individuals with autism spectrum disorders. The ...

An analysis of how synaptic proteins change during early development reveals differences between mice and marmosets but also what's different in individuals with autism spectrum disorders. The ...

A new study on the detriments of too many synaptic connections in the mouse cerebellum by neuroscientists at the Washington University School of Medicine in St. Louis corroborates previous human ...