A new spatial transcriptomic technology captures RNA patterns without requiring expensive imaging ...

Researchers have gained new insights into the mechanism behind the spatial organization of DNA within the cells of early embryos. When an embryo is first formed after fertilization, each cell has the ...

(A) Schematic of the experimental design and analysis. Paracancerous and cancer tissues obtained from surgically resected DLBCLs were split and processed for scRNA-seq and spatial transcriptomics. (B) ...

In a recent study published in Nature, researchers investigate the spatial organization of cancer cells and the tumor microenvironment by analyzing over one hundred tumor sections across six types of ...

Left: Imaging of lamin A/C structures in a physically expanded nucleus from an individual with progeria. Right: Same, but with 3D genomic reads overlaid in their original spatial locations, colored by ...

Spatial proteomics enables scientists to investigate protein organization at the subcellular, cellular, and tissue levels, including in pathological contexts. Using technologies that help researchers ...

An international research team has provided a detailed insight into how the spatial organization of genetic material is established in the cell nucleus of early embryos within the first hours after ...

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context. In musculoskeletal ...