Researchers in the Perelman School of Medicine at the University of Pennsylvania have identified a cell surface receptor ...

The data shows that inhibiting TIE2 with rebastinib could prevent new abnormalities from forming in the brain with fewer side effects.

New research links atopic dermatitis to S1P signalling pathways driving inflammation. Learn how this could shape future ...

Can we prevent brain hemorrhages without surgery? New research identifies TIE2 as a key driver of cerebral cavernous malformations (CCMs). Discover how the drug rebastinib could provide a safer, ...

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on ...

Researchers at Texas A&M Health have identified a molecular mechanism that increases cholesterol levels inside prostate ...

New research has identified a previously underexplored immune signalling pathway that could help explain persistent ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

Scientists discover gut cells that stop mosquitoes from biting after feeding, linking appetite, reproduction, and disease spread.