A new review links three forces shaping osteoarthritis: mechanical stress, integrin signaling, and integrin endocytosis. The ...

Inflammation drives TGFβ1 activation via the αvβ6 integrin-mechanotransduction pathway in human skin. Transforming growth factor β (TGFβ) is a critical regulator of skin home ...

Talin is a protein that plays an important role in the immune system by activating integrins, receptors that help cells attach to one another. Now a new study by Fox Chase Cancer Center researchers ...

Atherosclerosis represents a chronic inflammatory disease characterized by the accumulation of lipid-laden macrophage foam cells within arterial walls, serving as the underlying pathological basis for ...