Randomized trials of platelet function and genetic testing to guide antiplatelet decisions following PCI have produced notoriously mixed results: now, an updated consensus document aims to fill some ...

The coronavirus disease-19 (COVID-19) pandemic that emerged in Wuhan, China, in late December 2019 spread rapidly throughout the world and has caused over 6.5 million deaths. The disease is caused by ...

COVID-19 triggers hyperactivity in platelets leading to the formation of more blood clots in some patients. Photo credit: Getty Images Changes in blood platelets triggered by COVID-19 could contribute ...

One of the side effects of aspirin is reduced platelet function. Aspirin can potentially make issues with blood clotting worse. Thrombocytopenia is the medical term for low platelet count. Platelets ...

Ado-trastuzumab emtansine (T-DM1) treatment results in grade 3-4 thrombocytopenia in 8%-13% of patients. Prior in vitro studies reported T-DM1 inhibition of megakaryocyte maturation as the cause of ...

Intravital microscopy image from the liver of a mouse model: a platelet (turquoise) adheres to the inflamed vessel wall (yellow dashed outline) and sheds a long, filamentous membrane extension—a ...

Treating patients with acute respiratory failure is a constant challenge in intensive care medicine. In most cases, the underlying cause is lung inflammation triggered by a bacterial infection or - ...

What Is the Platelet Aggregation Test? A platelet aggregation test is a blood test that looks at how well your blood cells called platelets clump together and clot. It is sometimes called a platelet ...

Managing drug dosage is critical to the overall success of pharmaceutical intervention, not only in the clinic but also in clinical trials. Inadequate dose management of certain drugs can have fatal ...

Medically reviewed by Gagandeep Brar, MD Key Takeaways A high platelet count can lead to blood clots and bleeding, which can be dangerous. Reactive thrombocytosis is often linked to another cause of ...

A team from Würzburg has fundamentally changed our understanding of platelet biology with a study published in Science. The researchers demonstrate that the surface protein integrin αIIbβ3 is not only ...