CRISPR-Cas9 is widely used to edit the genome by studying genes of interest and modifying disease-associated genes. However, this process is associated with side effects including unwanted mutations ...

A novel genome editing technique, NICER, is based on the creation of multiple nicks in single DNA strands by nickase. The method can correct heterozygous mutations using two mechanisms: multiple nicks ...

A Penn State-led team of interdisciplinary researchers has developed techniques to improve the efficiency of CRISPR-Cas9, the genome editing technique that earned the Nobel Prize in 2020. While CRISPR ...

A powerful new approach for the precise, flexible modification of a broad class of chemical compounds called bicyclic aza-arenes—which are commonly used to build drug molecules—has been developed. The ...

Add Yahoo as a preferred source to see more of our stories on Google. Gene editing fixed brain mutations in mice with AHC, offering hope for treating rare neurological diseases at the DNA level.

PHILADELPHIA— A new approach to the genetic engineering of cells promises significant improvements in speed, efficiency, and reduction in cellular toxicity compared to current methods. The approach ...

Genetically modified organisms, also known as GMOs, have been a hot topic of conversation among researchers, producers, government agencies, and the general public for decades. GMOs are banned in some ...

A research team led by scientists from the Helmholtz Institute for RNA-based Infection Research (HIRI) has introduced a new way to fine-tune genetic material. Their study, published in Nature ...

Genetic editing holds promise to treat incurable diseases, but the most popular method — CRISPR — sometimes does more harm than good. A new study from University of California San Diego and Yale ...