New research from Dana-Farber Cancer Institute shows that a new class of drug results in cell death in cancers, such as small cell lung cancer, with a disabled quality control cell cycle checkpoint ...
Researchers in the lab of Jean Cook, Ph.D., chair and professor in the Department of Biochemistry and Biophysics, have identified the cellular processes that occur when you take a cancer drug meant to ...
This study presents a comprehensive investigation into the prognostic significance of CCCRGs in HCC. Notably, our research provides the first mechanistic evidence that CENPI promotes HCC malignant ...
A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the ...
KRAS G12D-targeted protein degrader setidegrasib showed antitumor activity with tolerable safety profile in patients with ...
Natural killer (NK) cells play an important role in the innate immune response to cancer and viral infections, and their presence in tumors correlates with improved patient outcomes in a variety of ...
Triple-negative breast cancer (TNBC) was first described as a distinct disease entity 20 years ago. Since that time, there has been tremendous effort invested in understanding the clinical features ...
A metabolic enzyme studied for over seven decades has a hidden second function - it can unwind RNA and promote cell cycle ...
The 2026 PSMA and Beyond conference featured an approaches to combination therapies session and presentation by Dr. Lawrence ...
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