Musculoskeletal disorders are a primary cause of disability worldwide, especially in aging societies like Japan. As ...

Osteogenesis imperfecta (OI) refers to a group of rare genetic bone disorders that results in the formation of fragile bones. In patients with OI, the matrix that makes up the bone has been found to ...

Gain-of-function mutations in fibroblast growth factor receptor (FGFR) genes are known to cause a range of skeletal disorders, such as craniosynostosis and chondrodysplasia, which severely affect ...

Cell- and animal-based models of bone formation reveal novel mechanisms involved in the cartilage-to-bone phenotype ...

A multisite, international phase 2 trial evaluating the investigational drug garetosmab has shown that it reduced soft-tissue flare-ups significantly and prevented new areas of abnormal bone formation ...

Obesity is widely known for increasing the risk of diabetes and cardiovascular disease, but its damaging effects on the ...

The GPR133 receptor is expressed by osteoblasts, the cells that make bone. The study suggests that this receptor helps those cells sense two kinds of input: mechanical strain and signals relayed by ...

BRISBANE, Calif.--(BUSINESS WIRE)--āshibio, a privately held biotechnology company developing novel therapeutics for the treatment of bone and connective tissue disorders, exited stealth mode today ...

Bone mineral density (BMD) appears to be preserved among patients with kidney failure who also have type 2 diabetes (T2D), according to study results published in the Journal of B ...

India, May 31 -- Parathyroid problems masquerade as common problems of many other organs, misleading many medical specialists. The parathyroid glands are endocrine organs that secrete the parathyroid ...