To evaluate the safety and early bactericidal activity of AZD5847 in subjects with sputum smear-positive pulmonary tuberculosis to better assess the potential role of this compound in TB treatment. To ...

Three years ago, Darren Cunningham, better known as Actress, released his fourth album. Ghettoville was a record that set off widespread speculation that it may in fact be his last, not least owing to ...

“I’m not a nerd, d’you know what I mean?” Darren Cunningham, the electronic artist known as Actress, is discussing the gaps in his knowledge of the ancient instruments, relics of the birth of techno ...

Darren Jordan Cunningham has been making boundary-pushing electronic music under the Actress name for well over a decade. His last album, 2014’s ‘Ghettoville’, was a dark, glitchy and soulful triumph.

About 30%-40% of triple-negative breast cancers (TNBC) show HER2-low status and may benefit from the HER2-directed antibody-drug conjugate trastuzumab deruxtecan (T-DXd). Ataxia-telangiectasia mutated ...

Researchers from Astrazeneca plc described the development and preclinical evaluation of AZD-5335, a novel antibody-drug conjugate (ADC) consisting of folate receptor α (FR-α)-targeting antibody ...