One of the surprises of the human genome project was that the number of genes discovered was considerably fewer than most had expected. I mean, for gosh sakes, we are at the top of the biological ...

Alternative splicing, a clever way a cell generates many different variations of messenger RNAs -- single-stranded RNAs involved in protein synthesis -- and proteins from the same stretch of DNA, ...

This article was review by Thomas Cooper, MD from Baylor College of Medicine. Stay up to date on the latest science with Brush Up Summaries. Despite its significance, alternative splicing’s global ...

Tokyo Medical and Dental University (TMDU) researchers harness long-read RNA sequencing to decode genetic intricacies and disease links. Alternative splicing, a process where a single gene can give ...

Previously, Chinese researchers used long-read RNA sequencing to identify a unique alternative splicing variant of CD44 transmembrane protein, named CD44E, which is highly expressed in hepatocellular ...

In a new study, researchers demonstrate that deregulation of a protein called RBFOX2, involved in RNA splicing, contributes to the progression and metastasis of pancreatic cancer. Pancreatic cancer ...

A wide spectrum of cancer-associated genetic alterations, including those that result in changes to the splicing of pre–messenger RNA (mRNA), can lead to the presentation of aberrant peptides as ...