In an ambitious collaboration, researchers added 1.8 million high-confidence protein complex structure predictions to the ...

Jacobs School researchers have shown how an electron diffraction technique can quickly and efficiently create high-resolution ...

Efforts to unlock the mysteries of proteins, building blocks of life, have earned three scientists the 2024 Nobel Prize in chemistry. The prize goes to David Baker “for computational protein design,” ...

Complex protein interactions at synapses are essential for memory formation in our brains, but the mechanisms behind these processes remain poorly understood. Now, researchers have developed a ...

The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion. While healthy transthyretin moves hormones through blood and spinal fluid, misfolded ...

In the wee hours of an October morning, David Baker, a protein biologist at the University of Washington (UW), received the most-awaited phone call in a scientist’s career. Halfway around the world, ...

Illustration showing how integrating protein three-dimensional structures with artificial intelligence algorithms can predict synergistic or antagonistic effects of drug combinations, guiding safer ...